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Medical Definition of Cholestyramine resin
1. A strongly basic anion-exchange resin in the chloride form, consisting of a copolymer of styrene and divinylbenzene with quaternary ammonium functional groups; it lowers the blood cholesterol by binding the bile acids in the intestine, thus promoting their excretion in the faeces instead of reabsorption from the bowel; used in the treatment of hypercholesterolaemia, xanthomatous biliary cirrhosis, and other forms of xanthomatosis. (05 Mar 2000)