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Definition of Cholic acid
1. Noun. An insoluble crystalline acid present in bile.
Definition of Cholic acid
1. Noun. (biochemistry) a steroidal bile acid, C24H40O5, derived from cholesterol ¹
¹ Source: wiktionary.com
Medical Definition of Cholic acid
1. A family of steroids comprising the bile acids (or salts), generally in conjugated form (e.g., glycocholic and taurocholic acids). Chemically, cholic acids are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a -COOH group); biologically, cholic acids are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several cholic acid; e.g., cholic acid is 3a,7a,12a-trihydroxy-5b-cholan-24-oic acid, deoxycholic acid is 3a,12a-dihydroxy-5b-cholanic acid. Synonym: cholalic acid, cholanic acid. (05 Mar 2000)
Lexicographical Neighbors of Cholic Acid
Literary usage of Cholic acid
Below you will find example usage of this term as found in modern and/or classical literature:
1. A Dictionary of Applied Chemistry by Thomas Edward Thorpe (1921)
"(1) cholic acid dissolves in cone. H2SO4 with a reddish yellow colour showing a
characteristic green ... cholic acid is formed in the liver and there ..."
2. American Druggist (1887)
"The bile of horned cattle and of dogs contains two acids, one of them called
tauro-cholic and the other glyco-cholic acid. When either of these is boiled ..."
3. First principles of chemistry for the use of colleges and schools: For the by Benjamin Silliman (1861)
"cholic acid.—The bile of animals is a solution of the soda or potash salts of two
... cholic acid is monobasic, and is represented by ..."
4. Hand-book of Chemistry by Leopold Gmelin, Henry Watts (1871)
"Appendix to cholic acid. ... it is a mil- ture of cholic acid and ... the former
having the composition of cholic acid, and the latter containing 2 atoms of ..."
5. Physiological chemistry: A Text-book and Manual for Students by Albert Prescott Mathews (1916)
"It is possible by feeding animals cholic acid to increase somewhat the amount of
taurocholic acid in the bile. The body seems to have a supply oí taurine in ..."
6. A Treatise on human physiology by John Call Dalton (1871)
"If boiled for a long time with a dilute solution of potassa, glyko-cholic acid
is decomposed with the production of two new substances; ..."
7. A Textbook of physiological chemistry by Olof Hammarsten (1906)
"According to the latest statements of LASSAR-COHN 2 three cholic acids may be
prepared from human bile, namely, ordinary cholic acid, ..."
8. A Text-book of Physiological Chemistry by Olof Hammarsten, Sven Gustaf Hedin (1914)
"According to the statements of LASSAR-COHN l three cholic acids may be prepared
from human bile, namely, ordinary cholic acid, ..."
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