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Definition of Side chain
1. Noun. (chemistry) in organic chemistry, that part of a molecule attached to some core structure; a radical ¹
2. Noun. (biochemistry) the variable parts of amino acids that extend from the peptide backbone in proteins; they are referred to as R-groups, which branch off the backbone at the alpha carbon (C?). ¹
¹ Source: wiktionary.com
Medical Definition of Side chain
1. A chain of noncyclic atoms linked to a benzene ring, or to any cyclic chain compound, the atoms of an alpha-amino acid other than the alpha-carboxyl group, the alpha-amino group, the alpha-carbon, and the hydrogen attached to the alpha-carbon. (05 Mar 2000)