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Medical Definition of Glutaryl-CoA
1. The mono thiol ester of coenzyme A and glutaric acid; an intermediate in l-lysine and l-tryptophan catabolism. Glutaryl-CoA dehydrogenase, an enzyme that catalyses the reaction of glutaryl-CoA with an acceptor to form crotonoyl-CoA, CO2, and the reduced acceptor; a deficiency of this enzyme will lead to either glutaric acidemia type I or hyperoxaluria type II. Glutaryl-CoA synthetase, an enzyme similar to acyl-CoA synthetase, but which splits ATP, GTP, or ITP to the nucleoside diphosphate and orthophosphate in acting on glutarate, thus forming glutaryl-Coa. (05 Mar 2000)
Lexicographical Neighbors of Glutaryl-CoA
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