Lexic.us

Definition of Glutathione peroxidase

1. Noun. An enzyme in the body that is a powerful scavenger of free radicals.

Medical Definition of Glutathione peroxidase

1. A detoxifying enzyme that eliminates hydrogen peroxide and organic peroxides. Glutathione is an essential cofactor for the enzyme and its reaction involves the oxidation of glutathione (GSH) to glutathione disulphide (GSSG). The GSSG is then reduced to GSH by glutathione reductase. Glutathione peroxidase, (GPX), has a selenocysteine residue in its active site. Three forms of the enzyme exist: cy toplasmic GPX, plasma GPX and phospholipid hydroperoxide GPX. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Glutathione Peroxidase

Literary usage of Glutathione peroxidase

Below you will find example usage of this term as found in modern and/or classical literature:

1. Oxygen/Nitrogen Radicals and Cellular Injury edited by Kenneth B. Adler, Robert D. Devlin, Val Vallyathan (2000)
"The enzymatic antioxidant mechanism contains various forms of Superoxide dismutases (SOD), catalase, and glutathione peroxidase (GSHPx), as well as the ..."

2. Nutrient Composition of Rations for Short-term, High-intensity Combat Operations by Fnb, Institute of Medicine (U. S.), High-stress Situations, Committee on Military Nutrition Research, National Academy of Sciences (2005)
"Improvements in peak oxygen uptake were significantly correlated with glutathione peroxidase activity only in the men supplemented with selenium. ..."

3. Mineral Tolerance of Animals by National Research Council (U. S.) (2005)
"Since the milestone discovery of selenium as an integral part of cellular glutathione peroxidase (Rotruck et al., 1973), significant progress has been made ..."

4. Children's Environmental Health Research: Indoor Mold and Children's Health edited by Allen Dearry, Gwen Collman (2000)
"... mice in the presence and absence of vitamin E. II: Effect of glutathione peroxidase. Arch Environ Health 33:292-296 (1978). 27. Calabrese EJ, Horton HM. ..."

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