Medical Definition of Dihydrolipoamide dehydrogenase
1.
An enzyme oxidizing dihydrolipoamide at the expense of NAD+; completes the oxidative decarboxylation of pyruvate; a part of several enzyme complexes (e.g., alpha-ketoglutarate dehydrogenase complex). Decreased activity leads to neuronal loss in brain resulting in psychomotor retardation.
Synonym: coenzyme factor, lipoamide dehydrogenase, lipoamide reductase (NADH), lipoyl dehydrogenase.
(05 Mar 2000)
Lexicographical Neighbors of Dihydrolipoamide Dehydrogenase
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