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Medical Definition of Bisphospoglycerate
1. Previously known as 1,3-diphosphoglycerate (1,3DPG), this molecule is the first molecule that generates ATP in glycolysis. Its phosphorylgroupgenerates a high-potential phosphorylated compound through a redoxreaction.1,3BPG is also responsible for the production of an allosteric effector of haemoglobin, 2, 3-bisphosphoglycerate (2, 3BPG). Inthis reaction, a phosphoryl group is transferred from 1,3BPG to the C-2of 3PG. This yields 2, 3BPG and a different 3PG molecule. (09 Oct 1997)