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Medical Definition of Schmidt-Thannhauser method
1. A method for fractionation of nucleic acid, based upon the fact that RNA but not DNA is hydrolyzed to nucleotides by alkali; RNA can be hydrolyzed in about 2 hours in 0.75 n NaOH, but 18 hours and 0.3 n NaOH usually are used. (05 Mar 2000)