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Medical Definition of Schmidt-Lanterman clefts
1. Funnel-shaped interruptions in the regular structure of the myelin sheath of nerve fibres, formerly interpreted as actual breaks in the sheath but shown by electron microscopy to correspond each to a strand of cytoplasm locally separating the two otherwise fused oligodendroglial (or, in peripheral nerves, Schwann cell) membranes composing the myelin sheath. Synonym: Lanterman's incisures, Schmidt-Lanterman clefts. (05 Mar 2000)