Medical Definition of Uroporphyrin-III C-methyltransferase
1.
From pseudomonas denitrificans; enzyme of the cobalamin biosynthetic pathway which catalyses the c methylation of uroporphyrinogen III; also catalyses both nad+ dependent oxidation of precorrin-2 to sirohydrochlorin and insertion of iron into it to produce siroheme; cysg gene is from E coli; product of coba gene of pseudomonas; do not confuse with coba gene product of salmonella typhimurium which yields ATP-corrinoid adenosyltransferase
Registry number: EC 2.1.1.107
Synonym: uroiii methyltransferase, uroporphyrinogen III methylase, sumt methyltransferase, s-adenosylmethionine-uroporphyrinogen III methyltransferase, cysg gene product, siroheme synthase, coba gene product, propionibacterium
(26 Jun 1999)
Lexicographical Neighbors of Uroporphyrin-III C-methyltransferase
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