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Medical Definition of Trimethoprim-sulfamethoxazole
1. A drug combination consisting of a dihydrofolate reductase inhibitor (trimethoprim) and a sulfonamide antibacterial drug (sulfamethoxazole). The drug combination is synergistic as the drugs interfere with two successive steps in the formation/utilization of folic acid by microorganisms. Used to treat many infectious diseases. (05 Mar 2000)
Lexicographical Neighbors of Trimethoprim-sulfamethoxazole
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