Lexic.us

Definition of Tolbutamide

1. Noun. Sulfonylurea; an oral antidiabetic drug (trade name Orinase) used in the treatment of adult-onset diabetes mellitus.

Definition of Tolbutamide

1. Noun. A drug that blocks potassium channels, used in the treatment of diabetes. ¹

¹ Source: wiktionary.com

Definition of Tolbutamide

1. [n -S]

Medical Definition of Tolbutamide

1. An oral hypoglycemic agent (a prescription drug that people take to lower the level of glucose in the blood). The pills work for some people whose pancreas still makes some insulin. They can help the body in several ways, such as by causing the cells in the pancreas to release more insulin. (09 Oct 1997)

Lexicographical Neighbors of Tolbutamide

Literary usage of Tolbutamide

Below you will find example usage of this term as found in modern and/or classical literature:

1. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"(a) The University Group Diabetes Program clinical trial has reported an association between the administration of tolbutamide and increased cardiovascular ..."

2. Diabetes in America by Ronald Aubert (1996)
"A preliminary assessment of the effect of tolbutamide suggests that it did not significantly alter the course of microvascular complications in comparison ..."

3. Handbook of Severe Disability: A Text for Rehabilitation Counselors, Other edited by Walter C. Stolov, Michael R. Clowers (2000)
"Elderly patients who are symptomatic (eg, spilling sugar in urine) are best treated with the short-acting agent tolbutamide. This agent does not often cause ..."

4. Mammalian Models for Research on Aging by Institute Of Laboratory Animal Resources, Bennett J. Cohen, National Research Council Staff (1981)
"Studies on diabetic syndrome and influences of longterm tolbutamide administration in Mongolian gerbils (Meriones unguiculatus). Endocrinol. ..."

5. Guide To Clinical Preventive Services by U. S. Preventive Services Task Force (1989)
"Ten-year follow-up of subjects with impaired glucose tolerance: prevention of diabetes by tolbutamide and diet regulation. Diabetes 1980; 29:41-9. 36. ..."

6. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"... sulfonylureas such as tolbutamide), and substituted phenols (eg, resorcinol and salicylamide). Derivatives of thiourea, including ..."

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