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Medical Definition of Thymic alymphoplasia
1. Hypoplasia with absence of Hassall's corpuscles and deficiency of lymphocytes in the thymus and usually in lymph nodes, spleen, and gastrointestinal tract; there is peripheral lymphopenia and often hypogammaglobulinaemia and absence of plasma cells; presents in early infancy with respiratory infections and leads to death within a few months. See: immunodeficiency with hypoparathyroidism. (05 Mar 2000)