Medical Definition of Serglycin

1. An intracellular proteoglycan, found particularly in the storage granules of connective tissue mast cells. The core protein consists of 153 amino acids with 24 serine glycine repeats between amino acids 89 and 137, hence the name. The serine glycine repeats are the linkage sites for _15 glycosaminoglycan chains that are either heparin or highly sulphated chondroitin sulphate. These negatively charged chains are thought to concentrate positively charged proteases, histamine and other molecules within the storage granules. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Serglycin

sergeants-at-arms
sergeants-major
sergeants major
sergeantship
sergeantships
sergeanty
sergeaunt
serged
sergeevite
serger
sergers
serges
serging
sergings
serglycin (current term)
serial
serial bond
serial bonds
serial comma
serial commas
serial extraction
serial file
serial files
serial film changer
serial interval
serial intervals
serial key
serial keys
serial killer

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