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Definition of Schick test
1. Noun. A skin test for immunity to diphtheria.
Medical Definition of Schick test
1. A test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 ml of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); individuals with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; individuals lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24 to 36 hours at the test site only and persisting for 4 to 5 days. Synonym: Schick method. (05 Mar 2000)
Lexicographical Neighbors of Schick Test
Literary usage of Schick test
Below you will find example usage of this term as found in modern and/or classical literature:
1. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1916)
"Med., 1916, xvi, 208) reports the results of the schick test on 132 normal,
healthy children at the Rochester Orphan Asylum. Of this number, 100 were again ..."
2. A Manual for Health Officers by Joseph Scott MacNutt (1915)
"APPENDIX J THE schick test A new agent in the control of diphtheria has been ...
It is known as the schick test for immunity. The reaction depends on the ..."
3. Epidemiology and public health: a text and reference book for physicians by Victor Clarence Vaughan (1922)
"This is now known as the schick test, and t has proved of the greatest value in
ascertaining those individuals who lave and those who have not antitoxin in ..."
4. Therapeutic Gazette (1921)
"In the Archives of Pediatrics for June, 1921, PARK states that the schick test
can be compared with vaccination. A positive Schick reaction or a successful ..."
5. International Medical and Surgical Surveyby American Institute of Medicine by American Institute of Medicine (1922)
"The schick test. Standardization of Diptheria Toxin for the Test and of Heated
Diphtheria Toxin for the Control; Methods of Diluting the Toxin. ..."
6. The Principles of Therapeutics by Oliver Thomas Osborne (1921)
"The test referred to is the schick test, which consists of injecting ^£0 of a
minimum fatal dose of diphtheria toxin for a 250 gram guineapig into the skin ..."
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