Medical Definition of Sch-23390
1.
8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol. A dopamine d1 receptor antagonist that has no effect or only very limited effect on dopamine d2 receptors. The compound has tranquillising effects, inhibits conditioned avoidance response, impairs memory acquisition, produces dose-dependent catalepsy, blocks central serotonin receptors, and reduces the lethal effects of cocaine.
Pharmacological action: antipsychotic agents, dopamine antagonists.
Chemical name: 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (R)-
(12 Dec 1998)
Lexicographical Neighbors of Sch-23390
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