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Medical Definition of Receptor mediated endocytosis
1. Endocytosis of molecules by means of a specific receptor protein that normally resides in a coated pit, but may enter this structure after complex formation occurs. The structure then forms a coated vesicle that delivers its contents to the endosome whence it may enter the cytoplasm or the lysosomal compartment. Many bacterial toxins and viruses enter cells by this route. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)