|
Medical Definition of Pemphigus vulgaris
1. A serious form of pemphigus, occurring in middle age, in which cutaneous flaccid acantholytic suprabasal bullae and oral mucosal erosions may be localised a few months before becoming generalised; blisters break easily and are slow to heal; results from the action of autoimmune antibodies that localise to intercellular sites of stratified squamous epithelium. (05 Mar 2000)