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Medical Definition of Nucleus centromedianus
1. A large, lentil-shaped cell group, the largest and most caudal of the intralaminar nuclei, located within the lamina medullaris interna of the thalamus between the mediodorsal nucleus and ventrobasal nucleus; so called by Luys because of its prominent appearance on frontal sections midway between the anterior and posterior pole of the human thalamus. The nucleus receives numerous fibres from the internal segment of the globus pallidus by way of the thalamic fasciculus, ansa lenticularis, and lenticular fasciculus as well as projections from area 4 of the motor cortex; its major efferent connection is with the putamen although collaterals reach broad areas of the cerebral cortex. Synonym: nucleus centromedianus, centre median de Luys, centrum medianum. (05 Mar 2000)