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Definition of Nnrti
1. Noun. An antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs.
Exact synonyms: Non-nucleoside Reverse Transcriptase Inhibitor
Specialized synonyms: Delavirdine, Rescriptor, Nevirapine, Viramune
Group relationships: Drug Cocktail, Haart, Highly Active Antiretroviral Therapy
Generic synonyms: Reverse Transcriptase Inhibitor
Specialized synonyms: Delavirdine, Rescriptor, Nevirapine, Viramune
Group relationships: Drug Cocktail, Haart, Highly Active Antiretroviral Therapy
Generic synonyms: Reverse Transcriptase Inhibitor
Medical Definition of Nnrti
1. A member of a class of compounds, including delavirdine, loviride and nevirapine, that acts to directly combine with and block the action of HIV's reverse transcriptase (see). In contrast, nucleoside analogs block reverse transcriptase by capping the unfinished DNA chain that the enzyme is constructing. NNRTIs have suffered from HIV's ability to rapidly mutate and become resistant to their effects. (09 Oct 1997)
Lexicographical Neighbors of Nnrti
| NK cell NK cells Nle NLN NLP nm NM NMDA NMDA receptor NMN | NMP NMR NMR NNE NNRTI NNRTI NNW NO No no | no(a) no-account no-brainer no-count no-frills(a) no-go no-goal no-good no-go area no-hit |
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