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Definition of NNRTI
1. Noun. An antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs.
Specialized synonyms: Delavirdine, Rescriptor, Nevirapine, Viramune
Group relationships: Drug Cocktail, Haart, Highly Active Antiretroviral Therapy
Generic synonyms: Reverse Transcriptase Inhibitor
Medical Definition of NNRTI
1. A member of a class of compounds, including delavirdine, loviride and nevirapine, that acts to directly combine with and block the action of HIV's reverse transcriptase (see). In contrast, nucleoside analogs block reverse transcriptase by capping the unfinished DNA chain that the enzyme is constructing. NNRTIs have suffered from HIV's ability to rapidly mutate and become resistant to their effects. (09 Oct 1997)
Lexicographical Neighbors of NNRTI
| NMEA NMHA NMI NMJ NMJs NMN NMP NMR NMR spectroscopy NMS | NN NNE NNH NNHs NNI NNRTI (current term) NNS NNTO NNTP NNW | NO NOAA NOAA Corps NOAD NOBO NOC NOD NODE NOD mice NOE |
Literary usage of NNRTI
Below you will find example usage of this term as found in modern and/or classical literature:
1. The Military Laws of the United States: Relating to the Army, Volunteers by United States, John F. Callan (1863)
"... of th« approbation of the Prc*iili<nt i« re-*nnrti»«l by thr I'1 Afrd. |x>4. of tb« ..."
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