Definition of Nimustine
1. Noun. A particular drug designed for use in chemotherapy. ¹
¹ Source: wiktionary.com
Medical Definition of Nimustine
1.
N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-n-(2-chloroethyl)-n-nitrosourea. Antineoplastic agent especially effective against malignant brain tumours. The resistance which brain tumour cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agent or with radiotherapy for the treatment of various neoplasms.
Pharmacological action: antineoplastic agent.
Chemical name: Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-
(12 Dec 1998)
Lexicographical Neighbors of Nimustine
Other Resources:
