Lexic.us

Definition of Naltrexone

1. Noun. An oral antagonist against the action of opiates.

Definition of Naltrexone

1. Noun. An opiate antagonist used to treat opioid dependence ¹

¹ Source: wiktionary.com

Definition of Naltrexone

1. [n -S]

Medical Definition of Naltrexone

1. Derivative of noroxymorphone that is the n-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence. Pharmacological action: narcotic antagonists. Chemical name: Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)- (12 Dec 1998)

Lexicographical Neighbors of Naltrexone

Literary usage of Naltrexone

Below you will find example usage of this term as found in modern and/or classical literature:

1. Overview of Addiction Treatment Effectiveness by Mim J. Landry (1996)
"Fifteen were prescribed naltrexone for 2 months, and 16 were provided with ... naltrexone did not appear to be superior to the placebo with regards to ..."

2. Preventing HIV Infection Among Injecting Drug Users in High Risk Countries by Institute of Medicine (U.S.), National Academies Press (U.S. (2007)
"Oral naltrexone provides relatively long-lasting (up 1-3 days depending on dose) ... New long-acting, injectable formulations of naltrexone produce adequate ..."

3. Treatment of Opiate Addiction Using Methadone: A Counselor's Manual by Michael J. McCann, Richard A. Rawson, Jeanne L. Obert (1995)
"naltrexone. The risks and uncertainties of the post-methadone period can be eliminated by going on the opiate blocker naltrexone, an oral prescription ..."

4. Problems of Drug Dependence: Proceedings of the 58th Annual Scientific Meeting by Louie S. Harrie (1999)
"On drug training days a single injection of naltrexone is administered during ... A variable number of saline cycles (0-5) precede the naltrexone cycle and ..."

5. Drug Abuse and Drug Abuse Research (1991): The Third Triennial Report to edited by MaryLouise Embrey, Christine R. Hartel (1999)
"naltrexone treatment started too soon after narcotic administration may ... This aversive reaction is a major obstacle to naltrexone's therapeutic use. ..."

6. Harmful Non-Indigenous Species in the United States (1994)
"Volpicelli, JR; Volpicelli, LA.; and O'Brien, CP Medical management of alcohol dependence: Clinical use and limitations of naltrexone treatment. ..."

7. Alcohol and the Brain (1993)
"Naloxone and naltrexone are two drugs that block opiate receptors, ... naltrexone has been used in heroin addicts to block the reinforcing effect of heroin ..."

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