Lexic.us

Definition of Nalorphine

1. Noun. A narcotic antagonist (trade name Nalline) that counteracts the effects of narcotics (especially the effects of poisoning by morphine).

Definition of Nalorphine

1. Noun. A drug used to reverse opioid overdose. ¹

¹ Source: wiktionary.com

Definition of Nalorphine

1. [n -S]

Medical Definition of Nalorphine

1. (5 alpha,6 alpha)-7,8-didehydro-4,5-epoxy-17-(2-propenyl)morphinan-3,6-diol. A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete. Pharmacological action: narcotic antagonists. Chemical name: Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)- (12 Dec 1998)

Lexicographical Neighbors of Nalorphine

Literary usage of Nalorphine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"Each milliliter of aqueous solution contains 5 milligrams of nalorphine hydrochloride. (b) Sponsor. See No. 050604 in §510.600(c) of this chapter. ..."

2. Problems of Drug Dependence: Proceedings of the 58th Annual Scientific Meeting by Louie S. Harrie (1999)
"... were full agonists, but nalorphine, diprenorphine and pentazocine were partial agonists. Nor-BNI and naloxone were antagonists devoid of activities. ..."

3. Science by American Association for the Advancement of Science (1883)
"... (nalorphine, Nal- line) would not be suitable for carrying out such extinction because early studies showed that, for chronic spinal dogs, this narcotic ..."

4. Harmful Non-Indigenous Species in the United States (1994)
"An investigation of nalorphine and perphenazine as negative reinforcers in an escape paradigm. Pharmacol Biochem Behav 6:61-71, 1977. ..."

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