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Medical Definition of Malariae malaria
1. A malarial fever with paroxysms that recur every 72 hours or every fourth day, reckoning the day of the paroxysm as the first; due to the schizogony and release of merozoites from infected cells, with invasion of new red blood corpuscles by Plasmodium malariae. Synonym: quartan fever, quartan malaria. (05 Mar 2000)