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Medical Definition of Klatskin's tumour
1. Adenocarcinoma of the common hepatic duct bifurcation. These tumours are generally small, sharply localised, and seldom metastasizing. G. Klatskin's original review of 13 cases was published in 1965. Once thought to be relatively uncommon, tumours of the bifurcation of the bile duct now appear to comprise more than one-half of all bile duct cancers. (12 Dec 1998)