Definition of Immunoglobulin E

1. Noun. One of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes.

Exact synonyms: Ige
Generic synonyms: Ig, Immune Gamma Globulin, Immune Globulin, Immune Serum Globulin, Immunoglobulin
Specialized synonyms: Reagin

Definition of Immunoglobulin E

1. Noun. (immunology) A class of antibody (or immunoglobulin "isotype") found in mammals. ¹

¹ Source: wiktionary.com

Medical Definition of Immunoglobulin E

1. Class of immunoglobulin (188 kD) associated with immediate type hypersensitivity reactions and helminth infections. Present in very low amounts in serum and mostly bound to mast cells and basophils that have an immunoglobulin E specific Fc receptor (FceR). Immunoglobulin E has a high carbohydrate content and is also present in external secretions. Heavy chain of epsilon type. (30 Mar 1998)

Lexicographical Neighbors of Immunoglobulin E

immunogenesis
immunogenetic
immunogeneticist
immunogenetics
immunogenic
immunogenically
immunogenicities
immunogenicity
immunogens
immunoglobin
immunoglobins
immunoglobular
immunoglobulin
immunoglobulin A
immunoglobulin D
immunoglobulin E (current term)
immunoglobulin G
immunoglobulin M
immunoglobulin allotypes
immunoglobulin constant region
immunoglobulin domains
immunoglobulin electrophoresis
immunoglobulin gm allotypes
immunoglobulin idiotypes
immunoglobulin inv allotypes
immunoglobulin isotypes
immunoglobulin joining region
immunoglobulin superfamily

Literary usage of Immunoglobulin E

Below you will find example usage of this term as found in modern and/or classical literature:

1. Otitis Media with Effusion in Young Children: Clinical Practice Guideline by Sylvan E. Stool (1998)
"(1983) reported on a prospective study of the role of hypersensitivity mediated by immunoglobulin E in the occurrence of otitis media with effusion. ..."

2. Proceedings of the Society for Experimental Biology and Medicine (1903)
"... 75 II stimulation of prolactin release by bicarbonate ion, 161, 495 propagation and characterization of myeloma cell line producing immunoglobulin E, ..."

3. Nutrient Composition of Rations for Short-term, High-intensity Combat Operations by Fnb, Institute of Medicine (U. S.), High-stress Situations, Committee on Military Nutrition Research, National Academy of Sciences (2005)
"... High stress Immunoglobulin A immunoglobulin E Insulin-like growth factor 1 Immunoglobulin M Interleukin Inducible nitric oxide synthase Institute of ..."

4. Latex Allergies and the Health Care Industry by Charlie Norwood (2000)
"immunoglobulin E (IgE) antibody-mediated hyper- sensitivity to natural rubber latex (latex) occurs in children with spina bifida who receive extensive latex ..."

5. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"... of four MM patients, had features indicative of asthma, with labile airway obstruction, and elevated serum immunoglobulin E and eosinophil levels. ..."

6. Meeting the Challenge: U. S. Industry Faces the 21st Century: The U. S by Jon Paugh (1998)
"... in population groups susceptible to the disease; and Genentech has an immunoglobulin E humanized monoclonal antibody (MAB) in phase II clinical trials. ..."

7. Mammalian Models for Research on Aging by Bennett J. Cohen, Institute Of Laboratory Animal Resources, National Research Council Staff (1981)
"... to be mediated by reaginic antibodies similar to human immunoglobulin-E, the type of mediator acting in certain forms of human asthma (Patterson et al., ..."

8. Understanding the Immune System by Lydia Woods Schindler (1991)
"Such allergic reactions are related to the antibody known as immunoglobulin E. Like other antibodies, each IgE antibody is specific; one reacts against oak ..."

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