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Medical Definition of Glutamate dehydrogenases
1. Enzymes that catalyze the reaction of l-glutamate, H2O, and NAD+ (or NADP+ in some cases) producing alpha-ketoglutarate (2-oxoglutarate), ammonia, and NADH; in mammals, this is the prime contributor to oxidative deamination. Synonym: glutamic acid dehydrogenases. (05 Mar 2000)