1. A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in gaucher's disease.
Chemical name: D-Glucosyl-N-acylsphingosine glucosylhydrolase
Registry number: EC 3.2.1.45
(12 Dec 1998)