|
Medical Definition of G(m3) ganglioside
1. N-acetylneuraminyl-galactosyl-glucosylceramide. This ganglioside is present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, g(m3):udp-n-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of g(m2) ganglioside from g(m3) ganglioside and is the cause of an anabolic sphingolipidosis. (12 Dec 1998)