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Medical Definition of Endothelin-2
1. A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts produced in the myocardium, placenta, and uterus, but the cells of origin are not clear. Endothelin-2 has no unique physiologic functions, as compared with endothelin-1. (n eng j med 1995;333(6):356-63) (12 Dec 1998)