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Definition of Complement membrane attack complex
1. Noun. (context: immunology) A formation of transmembrane channels on the surface of a pathogenic bacterial cell that disrupts the phospholipid bilayer of the target cell resulting in its destruction. ¹
¹ Source: wiktionary.com
Medical Definition of Complement membrane attack complex
1. The assembly of complement plasma glycoproteins c5b, c6, c7, c8, and polymeric c9 as a group on biological membranes. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The formation of the membrane attack complex is the terminal step in the complement cascade. (12 Dec 1998)
Lexicographical Neighbors of Complement Membrane Attack Complex
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