Lexic.us

Definition of Complement fixation

1. Noun. An immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination).

Medical Definition of Complement fixation

1. Binding of complement as a result of its interaction with immune complexes (the classical pathway) or particular surfaces (alternative pathway). This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Complement Fixation

Literary usage of Complement fixation

Below you will find example usage of this term as found in modern and/or classical literature:

1. The Journal of Infectious Diseases by Infectious Diseases Society of America, John Rockefeller McCormick Memorial Fund, John McCormick Institute for Infectious Diseases (1915)
"complement fixation IN THE DIAGNOSIS OF GONOCOCCAL INFECTIONS * ERNEST E. IRONS AND ... METHODS In making the complement fixation tests an antihuman rabbit ..."

2. Chemical Abstracts by American Chemical Society (1916)
"for 30 min., complement fixation occurred in 38-49% of sera. With both active and inactive sera the highest percentage of positive reactions was observed ..."

3. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1916)
"have been found by means of complement-fixation, this test was applied, but although the tests were carried out in various ways, there was no evidence of ..."

4. Principles of Immunology by Howard Thomas Karsner, Enrique Eduardo Ecker (1921)
"ACTIVATION BY COMPLEMENT. FIXATION OF THE COMPLEMENT OF NATURAL HEMOLYSINS. INHIBITION OF COMPLEMENT OTHER THAN BY FIXATION. ANTI-COMPLEMENTARY CHEMICAL ..."

5. Infection and Resistance: An Exposition of the Biological Phenomena by Hans Zinsser (1918)
"On the basis of their experience with bacterial extracts Wassermann and Bruck s then determined that complement fixation could ..."

Other Resources: