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Definition of Carcinoma in situ
1. Noun. A cluster of malignant cells that has not yet invaded the deeper epithelial tissue or spread to other parts of the body.
Medical Definition of Carcinoma in situ
1. Cancer that involves only the cells in which it began and has not spread to other tissues. Lobular carcinoma in situ is found in the lobules of the breast. Ductal carcinoma in situ (also called intraductal carcinoma) arises in the ducts. (16 Dec 1997)