Medical Definition of Anthramycin
1.
3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1h-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-2-propenamide. A broad-spectrum spectrum antineoplastic antibiotic isolated from streptomyces refuineus var. Thermotolerans. It has low toxicity, some activity against trichomonas and endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.
Pharmacological action: antibiotics, antineoplastic.
Chemical name: 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
(12 Dec 1998)
Lexicographical Neighbors of Anthramycin
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