Medical Definition of Adrenal leukodystrophy

1. Sudanophilic leukodystrophy with bronzing of skin and adrenal atrophy. A metabolic disorder of young males, characterised by widespread myelin degeneration and associated adrenal insufficiency. The myelin degeneration is massive in various portions of the brain and sometimes the spinal cord, with the accumulation of degradation products of myelin in macrophages: sudanophilic demyelination; atrophy is present in the adrenal glands and testes, and markedly increased amounts of very long-chain fatty acid are present in both the brain and adrenal glands. Symptoms include bronzing of the skin, dysarthria, cortical blindness, bilateral hemiplegia, pseudobulbar paralysis, and progressive dementia. Probably sex-linked recessive inheritance. (05 Mar 2000)

Lexicographical Neighbors of Adrenal Leukodystrophy

adrenal cortical steroid
adrenal cortical syndrome
adrenal crisis
adrenal cyst
adrenal gland
adrenal gland
adrenal gland hypofunction
adrenal gland insufficiency
adrenal gland tumour
adrenal haemorrhage
adrenal hermaphroditism
adrenal hyperplasia
adrenal hypertension
adrenal imaging
adrenal insufficiency
adrenal leukodystrophy (current term)
adrenal mass
adrenal medulla
adrenal medulla
adrenal medullary imaging
adrenal myelolipoma
adrenal rest
adrenal rest tumour
adrenal virilism
adrenal virilizing syndrome
adrenal weight factor
adrenarche
adrenarche
adrenergic
adrenergic

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