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Medical Definition of Acrosclerosis
1. Stiffness and tightness of the skin of the fingers, with atrophy of the soft tissue and osteoporosis of the distal phalanges of the hands and feet; a limited form of progressive systemic sclerosis occurring with Raynaud's phenomenon. See: CREST syndrome. Synonym: acroscleroderma, sclerodactyly, sclerodactylia. (05 Mar 2000)