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Medical Definition of Virchow's disease
1. A condition, either congenital or acquired, in which the head is abnormally large; usually applied to an adult skull with a capacity of over 1450 ml. Synonym: leontiasis ossea, macrocephaly, macrocephalia, megacephalia, megalocephaly, megalocephalia, Virchow's disease. Origin: mega-+ G. Kephale, head (05 Mar 2000)