Definition of Parkinson's disease

1. Noun. A degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.


Medical Definition of Parkinson's disease

1. A progressive, neurological disease first described in 1817 by James Parkinson. The pathology is not completely understood, but there appears to be consistent changes in the melanin-containing nerve cells in the brainstem (substantia nigra, locus coeruleus), where there are varying degrees of nerve cell loss with reactive gliosis along with eosinophilic intracytoplasmic inclusions (Lewy bodies). Biochemical studies have shown below normal levels of dopamine in the caudate nucleus and putamen. Symptoms include shuffling gait, stooped posture, resting tremor, speech impediments, movement difficulties and an eventual slowing of mental processes and dementia. (27 Sep 1997)

Lexicographical Neighbors of Parkinson's Disease

parkin
parking
parkings
parking area
parking brake
parking facilities
parking lot
parking meter
parking space
parking ticket
parking zone
parkins
Parkinson
Parkinson's
Parkinson's disease
Parkinson's disease
Parkinson's facies
Parkinson's law
Parkinson's syndrome
Parkinsonia
parkinsonian
parkinsonian
Parkinsonia aculeata
Parkinsonia florida
parkinsonism
Parkinsonism
parkinsonisms
parkinson disease
parkis
parkish

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