|
Medical Definition of O-phosphocholine
1. (CH3)3N+-CH2 CH2-OPO3 H-; choline O-phosphate;important in choline metabolism, e.g., as in cytidinediphosphocholine and in the biosynthesis of lecithins. Synonym: O-phosphocholine, phosphorylcholine. Phosphocholine cytidylyltransferase, an enzyme that catalyses the reaction of phosphocholine with CTP to form pyrophosphate and CDP-choline; the rate-limiting step of lecithin biosynthesis; the cytosolic form of the enzyme is inactive (a phosphorylated form of the enzyme). Phosphocholine diacylglycerol transferase, an enzyme in lecithin biosynthesis that catalyses the reaction of 1,2-diacylglycerol with CDP-choline to form CMP and phosphatidylcholine. (05 Mar 2000)