Medical Definition of O-succinylbenzoic acid synthase
1.
E coli enzyme; with shchc synthase catalyses formation of o-succinylbenzoic acid from isochorismic acid and alpha-ketoglutarate in presence of thiamine pyropyrophosphate; succinic semialdehyde anion is formed by decarboxylation of alpha-ketoglutarate by thiamine pyrophosphate; anion then attacks isochorismic acid, initiating aromatization with elimination of pyruvate and h2o
Registry number: EC 4.1.99.-
Synonym: ortho-succinylbenzoic acid synthase, osb synthase, 2-succinylbenzoic acid synthase
(26 Jun 1999)
Lexicographical Neighbors of O-succinylbenzoic Acid Synthase
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