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Medical Definition of Mohs' micrographic surgery
1. A technique for removal of skin tumours with a minimum of normal tissue, by prior necrosis with zinc chloride paste, mapping of the tumour site, and excision and microscopic examination of frozen section of thin horizontal layers of tissue, until all of the tumour is removed. More recently, the preliminary step of chemical necrosis has been omitted. Synonym: microscopically controlled surgery, Mohs' micrographic surgery, Mohs' surgery. (05 Mar 2000)