Medical Definition of Leber's hereditary optic atrophy

1. Hereditary degeneration of the optic nerve and papillomacular bundle with resulting rapid loss of central vision, progressive for several weeks, then usually stationary with permanent central scotoma; age of onset is variable, most often in the third decade; more males than females are affected and transmission is cytoplasmic and strictly on the female side. Mutation on the mitochondrial chromosome involved, which presumably interacts with an X-linked mutant. This mechanism may explain the bizarre sex ratio, which differs significantly from one country to another. (05 Mar 2000)

Lexicographical Neighbors of Leber's Hereditary Optic Atrophy

leavy
leaze
leazes
Lebanese
Lebanese Hizballah
Lebanese monetary unit
Lebanese pound
Lebanese Republic
Lebanon
lebbek
lebbeks
leben
lebens
lebensraum
lebensraums
Leber's hereditary optic atrophy
Leber's idiopathic stellate neuroretinitis
Leber's idiopathic stellate retinopathy
Leber's plexus
lebetase
Lebistes
Lebistes reticulatus
lebkuchen
Leboyer method
Leboyer method of childbirth
lecama
lecanomancy
lecanopteris
lecanora
Lecanoraceae

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