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Medical Definition of Le Bel-van't Hoff rule
1. The number of stereoisomers of an organic compound is 2n where n represents the number of asymmetric carbon atoms (unless there is an internal plane of symmetry). A corollary of their simultaneously announced conclusions, in 1874, that the most probable orientation of the bonds of a carbon atom linked to four groups or atoms is toward the apexes of a tetrahedron, and that this accounted for all then-known phenomena of molecular asymmetry (which involved a carbon atom bearing four different atoms or groups). See: stereoisomerism. (05 Mar 2000)
Lexicographical Neighbors of Le Bel-van't Hoff Rule
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