Medical Definition of IL-1

1. A soluble protein (17 kD: 152 amino acids) secreted by monocytes, macrophages or accessory cells involved in the activation of both T-lymphocytes and B lymphocytes and potentiates their response to antigens or mitogens. Its biological effects include the ability to replace macrophage requirements for T-cell activation, as well as affecting a wide range of other cell types. at least two IL-1 genes are active and alpha and beta forms of IL-1 are recognised. It is released early in an immune system response by monocytes and macrophages. It stimulates T-cell proliferation and protein synthesis. Another effect of IL-1 is that it causes fever. See: catabolin, endogenous pyrogen. Acronym: IL-1 (12 Dec 1998)

Lexicographical Neighbors of IL-1

II Peter
II Samuel
II Thessalonians
II Timothy
IJDB
IJN
IJP
IJS
IJssel
IJssel river
IJsselmeer
IKEA
IKIWISI
IKR
IL
IL-1 (current term)
IL-10
IL-11
IL-12
IL-13
IL-14
IL-15
IL-16
IL-2
IL-3
IL-4
IL-5
IL-6
IL-7
IL-8

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