Definition of Coxsackie virus
1. Noun. Enterovirus causing a disease resembling poliomyelitis but without paralysis.
Medical Definition of Coxsackie virus
1.
A group of picornaviruses, included in the genus Enterovirus, first isolated in a village called Coxsackie, New York, USA.
Coxsackie virus has a spherical shape, about 28 nm in diameter, and causes myositis, paralysis, and death in young mice, and is responsible for a variety of diseases in man, and probably accounts for as many as 50% of all cases of viral pericarditis and myocarditis. Other infections include; herpangina, aseptic meningitis, a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia, and a serious myocarditis. Also causes hand, foot and mouth disease.
They are divided antigenically into two groups, A and B, each of which includes a number of serological types.
Coxsackie A viruses are divided into 24 serotypes and are associated with or implicated in herpangina, hand-foot-and-mouth disease, aseptic meningitis, paralytic disease, encephalitis, ataxia, acute onset juvenile diabetes, and cardiac diseases with diffuse myositis. Coxsackie A24 variant can cause acute haemorrhagic conjunctivitis.
Coxsackie B is divided into 6 serotypes and associated with epidemic pleurodynia (b1, b3), myocarditis and endocarditis (b3, b1), respiratory disorders (b3, b5), and kidney, pancreas, and liver disorders. It can also produce focal areas of degeneration in brain and skeletal muscle. Similar to polioviruses in chemical and physical properties.
Origin: Coxsackie, N.Y., where first isolated
(08 Mar 2000)
Lexicographical Neighbors of Coxsackie Virus
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