Definition of Myasthenia gravis

1. Noun. A chronic progressive disease characterized by chronic fatigue and muscular weakness (especially in the face and neck); caused by a deficiency of acetylcholine at the neuromuscular junctions.


Medical Definition of Myasthenia gravis

1. The characteristic feature of the disease is easy fatigue of certain voluntary muscle groups on repeated use. Muscles of the face or upper trunk are especially likely to be affected. In most and perhaps all cases due to the development of autoantibodies against the acetylcholine receptor in neuromuscular junctions. Immunisation of mice or rats with this receptor protein leads to a disease with the features of myasthenia. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Myasthenia Gravis

myalgia thermica
myalgias
myalgic
myalgic encephalomyelitis
myalism
myalisms
myall
myall wood
myalls
myanmar
myaria
myases
myasis
myasthenia
myasthenia gravis (current term)
myasthenia gravis and thymoma
myasthenias
myasthenic
myasthenic crisis
myasthenic facies
myasthenic reaction
myasthenic syndrome
myasthenics
myatonia
myatrophy
myb
myc
myc proteins

Literary usage of Myasthenia gravis

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"1721 East Madison Street, Maryland 21205 myasthenia gravis is a neuromuscular disorder ... In order to understand the pathogenesis of myasthenia gravis, ..."

2. Journal of Nervous and Mental Disease by Philadelphia Neurological Society, American Neurological Association, Chicago Neurological Society, New York Neurological Association (1915)
"affection might be considered a form of myasthenia gravis. ... It is, however, exceedingly unusual that the weakness in myasthenia gravis is limited ..."

3. Journal of Nervous and Mental Disease by American Neurological Association, Philadelphia Neurological Society, Chicago Neurological Society, New York Neurological Association, Boston Society of Psychiatry and Neurology (1915)
"affection might be considered a form of myasthenia gravis. ... It is, however, exceedingly unusual that the weakness in myasthenia gravis is limited ..."

4. The Principles and Practice of Medicine: Designed for the Use of by William Osler (1912)
"... and considered the names of four somewhat similar affections as synonyms of the same. VI. myasthenia gravis (Asthénie Bulbar Paralysis; ..."

5. Thyroid and Thymus by André Crotti (1922)
"Oppenheimer, Weigert, Lacquer and Buzzard thought these tumors were associated with myasthenia gravis. In all cases of myasthenia gravis, Mendelbaum and ..."

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