Medical Definition of Acute non-lymphocytic leukaemia

1. A form of leukaemia which is characterised by the proliferation of immature bone marrow precursor cells in the marrow and immature white blood cells (granulocytes) in the bloodstream. Occurs primarily in adults and in infants under 1 year of age. Complications include abnormal bleeding and susceptibility to infections. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Trisomy-8 is the most common cytogenetic abnormality observed, followed by monosomy-7 and monosomy-5. Approximately 8% of cases show trisomy-8, mostly in AML (M1), AM (M4) and acute monocytic leukaemia (M5). Many pre-leukaemic conditions, acute non-lymphocytic leukaemia and secondary leukemia show monosomy-7 or deletion of the long arm of chromosome 7. Treatment includes chemotherapy and/or bone marrow transplant. Acronym: ANLL Incidence: 2.5 cases per 100,000 (all ages). Origin: Gr. Haima = blood (07 Apr 1998)



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Lexicographical Neighbors of Acute Non-lymphocytic Leukaemia

acute mountain sickness
acute myeloblastic leukaemia
acute myelocytic leukemia
acute myelogenous leukaemia
acute myeloid leukaemia
acute myeloid leukemia
acute necrotising ulcerative gingivitis
acute necrotizing encephalitis
acute necrotizing haemorrhagic encephalomyelitis
acute necrotizing haemorrhagic leukoencephalitis
acute necrotizing ulcerative gingivitis
acute nephritic syndrome
acute nephritis
acute nephrosis
acute non-lymphocytic leukaemia (current term)
acute organic brain syndrome
acute pancreatitis
acute parenchymatous hepatitis
acute porphyria
acute post-streptococcal glomerulonephritis
acute primary haemorrhagic meningoencephalitis
acute promyelocytic leukaemia
acute pulmonary alveolitis
acute pulmonary eosinophilia
acute pyelonephritis
acute radiation syndrome
acute reflex bone atrophy
acute rejection
acute renal failure

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