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Medical Definition of Vasoactive intestinal polypeptide
1. A polypeptide hormone secreted most commonly by non-beta islet cell tumours of the pancreas, producing copious watery diarrhoea and faecal electrolyte loss, particularly hypokalaemia; VIP increases the rates of glycogenolysis; stimulates pancreatic bicarbonate secretion. Synonym: vasoactive intestinal peptide. (05 Mar 2000)