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Medical Definition of Vanillylmandelic acid test
1. A test for catecholamine-secreting tumours (pheochromocytoma and neuroblastoma) performed on a 24-hr urine specimen; it is based on the fact that vanillylmandelic acid is the major urinary metabolite of norepinephrine and epinephrine. Synonym: 3-methoxy-4-hydroxymandelic acid test, VMA test. (05 Mar 2000)